Nicotine Addiction

Nicotine addiction—classified under tobacco use disorder—is a chronic brain condition characterized by compulsive nicotine use, despite knowing the harmful health consequences. Nicotine, the primary addictive chemical in tobacco products, produces both physical dependence and strong psychological cravings.

Nicotine triggers the release of neurotransmitters like dopamine, creating pleasurable sensations that reinforce continued use. Over time, users develop tolerance, needing more nicotine to achieve the same effect, and experience withdrawal symptoms when they try to quit.

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FREQUENTLY ASKED QUESTIONS

Nicotine ranks among the most addictive substances, on par with heroin and cocaine, because of how strongly it activates the brain’s reward pathways.
Acute withdrawal peaks within 2-3 days and can last a few weeks, though cravings and mood changes may persist for months.
While vaping exposes users to fewer toxic substances than cigarettes, it still delivers addictive nicotine and harmful chemicals. It’s not risk-free.
Some people quit “cold turkey,” but success rates are higher with support, counseling, and medications.

KEY TERMS

Nicotine Addiction

Chronic dependence on nicotine, leading to compulsive use and withdrawal symptoms.

Dopamine

Neurotransmitter involved in pleasure and reward, heavily influenced by nicotine use.

Nicotine Replacement Therapy (NRT)

Medical products delivering low doses of nicotine to help people quit smoking.

Varenicline

Prescription medication that reduces nicotine cravings and blocks its pleasurable effects.

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